BRONCHIAL ASPIRATES GLUCOSE LEVEL AS INDICATOR FOR METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) IN INTUBATED MECHANICALLY VENTILATED PATIENTS

Document Type : Original Article

Authors

1 Department of Chest, Faculty of Medicine, El Fayoum University, Egypt.

2 Department of Biochemistry, Faculty of Medicine, Cairo University, Egypt.

3 Department of Internal Medicine, Faculty of Medicine, Al Azhar University, Egypt.

4 Department of Anesthesia, Faculty of Medicine, Cairo University, Egypt.

Abstract

This study evaluated if the level of glucose in bronchial aspirate serves as indicator for the risk of MRSA infection in intubated mechanically ventilated ICU patients. A total of 50 critically ill patients was enrolled and were under tight glycemic control to abolish the effect of hyperglycemia on bronchial secretion, if they were expected to require mechanical
ventilation for more than 48 hours. Bronchial aspirates were detected for glucose and sent twice weekly for microbiological analysis and whenever an MRSA was expected. The results showed that all the patients had glucose tested in bronchial aspirates. Glucose was detected in bronchial aspirates of 28 of the 50 patients. Glucose in bronchial aspirates in these
patients ranged between (2.9-5.1mmol/l). MRSA was detected in 22 patients where 28 were MRSA free of the MRSA patients 19 had positive glucose where glucose was positive in 28 patients of them 19 (86.4%)where MRSA positive to 9 with no MRSA (32.1%).The risk of having MRSA present markedly increased significantly in the presence of glucose: (p value .001)

Keywords

Journal of the Egyptian Society of Parasitology
Volume 44, Issue 2
August 2014
Pages 381-388

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