• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Journal of the Egyptian Society of Parasitology
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 50 (2020)
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 49 (2019)
Volume Volume 48 (2018)
Volume Volume 47 (2017)
Volume Volume 46 (2016)
Volume Volume 45 (2015)
Volume Volume 44 (2014)
Volume Volume 43 (2013)
EL AMIR, A., FARID, A., MOHAMED, M., RAMADAN, W., DIAB, A. (2020). THE EFFICACY OF DIZYGTHECA KERCHOVEANA AND AZADIRACHTA INDICA EXTRACTS AS A MOLLUSCICIDAL AND SCHISTOSOMICIDAL AGENTS IN MICE. Journal of the Egyptian Society of Parasitology, 50(1), 79-86. doi: 10.12816/jesp.2020.88757
AZZA M. EL AMIR; ALYAA A. FARID; MARIAM MOHAMED; WAAD RAMADAN; AYMAN ALI DIAB. "THE EFFICACY OF DIZYGTHECA KERCHOVEANA AND AZADIRACHTA INDICA EXTRACTS AS A MOLLUSCICIDAL AND SCHISTOSOMICIDAL AGENTS IN MICE". Journal of the Egyptian Society of Parasitology, 50, 1, 2020, 79-86. doi: 10.12816/jesp.2020.88757
EL AMIR, A., FARID, A., MOHAMED, M., RAMADAN, W., DIAB, A. (2020). 'THE EFFICACY OF DIZYGTHECA KERCHOVEANA AND AZADIRACHTA INDICA EXTRACTS AS A MOLLUSCICIDAL AND SCHISTOSOMICIDAL AGENTS IN MICE', Journal of the Egyptian Society of Parasitology, 50(1), pp. 79-86. doi: 10.12816/jesp.2020.88757
EL AMIR, A., FARID, A., MOHAMED, M., RAMADAN, W., DIAB, A. THE EFFICACY OF DIZYGTHECA KERCHOVEANA AND AZADIRACHTA INDICA EXTRACTS AS A MOLLUSCICIDAL AND SCHISTOSOMICIDAL AGENTS IN MICE. Journal of the Egyptian Society of Parasitology, 2020; 50(1): 79-86. doi: 10.12816/jesp.2020.88757

THE EFFICACY OF DIZYGTHECA KERCHOVEANA AND AZADIRACHTA INDICA EXTRACTS AS A MOLLUSCICIDAL AND SCHISTOSOMICIDAL AGENTS IN MICE

Article 10, Volume 50, Issue 1, Spring 2020, Page 79-86  XML PDF (672.97 K)
Document Type: Original Article
DOI: 10.12816/jesp.2020.88757
Authors
AZZA M. EL AMIR1; ALYAA A. FARID1; MARIAM MOHAMED2; WAAD RAMADAN2; AYMAN ALI DIAB2
1Department of Zoology, Faculty of Science, Cairo University, Egypt.
2Department of Zoology, Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), Egypt.
Abstract
In the present study, the effect of methanol extracts of two plant species, Dizygotheca kerchoveana (Maliaceae) and Azadirachta indica (Araliacaea) were tested on the activity of Schistosoma mansoni worms. Efficacy of two plant extracts compared with praziquantel (PZQ) was evaluated in vivo. The results showed that reduction was 90% in case of PZQ treatment compared to 76.91%, 62.64% after treatment with D. kerchoveana and A. indica extracts respectively. PZQ recorded highest significant number of dead ova into oogram pattern (80±1.80) at 5wk PI. But, good results were obtained by of D. kerchoveana and A. indica methanol extracts (65.00±4.05 & 60.60±3.60, respectively) at 3wk PI. Efficacy of the plant extract showed a significant (P<0.01) reduction in ova to 91-96.20% in intestine, 83.36-91.24% in hepatic tissues as compared to PZQ (10-66.50% & 1.14-80.64%, respectively). Reduction in hepatic granuloma
diameter at 3wk PI was significantly (P<0.01) reduced in group treated with D. kerchoveana (40.43% & 38.30%) as compared to PZQ (8.70% & 11.7%). Sera were assayed by ELISA for IgM & IgG levels. Highly significant (P<0.01) increase in Igs levels in all infected treated or untreated groups was at 3wk & 5wk PI as compared to normal mice.
Keywords
S. mansoni; PZQ; methanol plant extracts; Hepatic granuloma; IgM; IgG
Statistics
Article View: 67
PDF Download: 157
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.