LARVICIDAL EFFICACY OF HYPTIS PECTINATA LEAF EXTRACTS AGAINST AEDES AEGYPTI 4TH INSTAR LARVAE IN NIGERIA

NWASO, BLESSING C.; IKUESAN, ADENIRAN J.; IZEKOR, ESE S.; AJAEGBU, EZE E.; BELLO, ABDULRASHEED M.; OKOLO, IJEOMA O.; BASSEY, NNYENEIME U.; EZEH, UKACH-UKWU C.; DIEKE, ADAOBI J.; NWOBODO, CHINENYE A.; NDUKA, FLORENCE O.

doi:10.21608/jesp.2024.397265

LARVICIDAL EFFICACY OF HYPTIS PECTINATA LEAF EXTRACTS AGAINST AEDES AEGYPTI 4TH INSTAR LARVAE IN NIGERIA

Document Type : Original Article

Authors

¹ Department of Applied Sciences, Federal College of Dental Technology and Therapy, Trans-Ekulu Enugu State, Nigeria

² Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, David Umahi Federal University of Health Sciences, Uburu Ebonyi State, Nigeria

10.21608/jesp.2024.397265

Abstract

Yellow fever, Dengue fever, Chikungunya, and Zika virus are risky Aedes aegypti-borne infectious
diseases among natives and travelers who travel to endemic countries globally. A total of 10g of each
rigorously weighed dried leaf of Hyptis pectinata and four extracts (hexane, DCM, acetone, &ethanol)
at concentrations of 125, 250, 500, & 1000ppm were evaluated for larvicidal activities against Ae. ae
gypti 4th instar larvae.
LC50 mortality increased to 100%, 20%, 60%, & 60% at 500ppm of hexane, DCM, acetone, and eth
anol extract (171, 203, 419 & 449 ppm, respectively), after 24 hours laboratory exposure. This inex
pensive medicinal plant reduced mosquitoes and thus can control their infectious parasitic and viral
diseases.

Keywords