IN VITRO STUDY ON THE ANTIPARASITIC EFFECT OF OMEPRAZOLE ON CRYPTOSPORIDIUM PARVUM

Document Type : Original Article

Authors

1 Department of Medical Parasitology, Faculty of Medi cine, Tanta University, Egypt

2 Department of Histology, Faculty of Medi cine, Tanta University, Egypt

3 Department of Histology and Anatomy, Mutah University, Mutah, Jordan

4 Department of Medical Parasitology Faculty of Medicine, Alexandria University, Egypt

Abstract

Cryptosporidiosis is an important zoonotic diarrheal disease of worldwide distribution in man 
animals as well water canals, causing about one million deaths annually. This study investigated 
the anti-parasitic and anti-inflammatory effects of omeprazole versus nitazoxanide and as a 
combined therapy to treat Cryptosporidium parvum infection in tissue culture. Histopathological 
and SEM examinations on infected tissue cultures evaluated treatment. 
The results showed marked treated and inflammation improvement with omeprazole over nita
zoxanide combined treatment as indicated by histopathological and SEM studies.

Keywords

Journal of the Egyptian Society of Parasitology
Volume 54, Issue 3
December 2024
Pages 453-458

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