VONOPRAZAN VERSUS PROTON PUMP INHIBITORS IN COMBINATION WITH ANTIBIOTICS AS A TRIPLE THERAPY FOR ERADICATION OF CLARITHROMYCIN RESISTANT STRAIN OF HELICOBACTER PYLORI
Generally, the common etiology of gastritis infection with Helicobacter pylori (H. pylori) is increasing. Vonoprazan inhibits the activity of H+/K+ ATPases, with greater effect than PPIs on decreasing gastric acidity. This randomized controlled study was performed on two Egyptian patients groups: G1: 160 patients treated with Vonoprazan, Levofloxacin and Amoxicillin for two weeks, and G2: 160 pat-ients treated with Pantoprazole, Levofloxacin andAmoxicillin for two weeks. Testing fecal H. pylori Ag for all patients was done 8 weeks later after the completion of treatment course. The results showed that 136 of 160(85%) patients were negative for H. pylori Ag in G1 compared to 112/160(70%) patients in G2 with the In intention to treat (ITT) analysis and per-protocol (PP) analysis, for eradication rates was in G1greater than in G2 (P = 0.004, 0.002), respectively.
Elfors, M., & NAGUIB, A. (2024). VONOPRAZAN VERSUS PROTON PUMP INHIBITORS IN COMBINATION WITH ANTIBIOTICS AS A TRIPLE THERAPY FOR ERADICATION OF CLARITHROMYCIN RESISTANT STRAIN OF HELICOBACTER PYLORI. Journal of the Egyptian Society of Parasitology, 54(2), 313-318. doi: 10.21608/jesp.2024.373534
MLA
Mostafa Elfors; AHMED M. NAGUIB. "VONOPRAZAN VERSUS PROTON PUMP INHIBITORS IN COMBINATION WITH ANTIBIOTICS AS A TRIPLE THERAPY FOR ERADICATION OF CLARITHROMYCIN RESISTANT STRAIN OF HELICOBACTER PYLORI". Journal of the Egyptian Society of Parasitology, 54, 2, 2024, 313-318. doi: 10.21608/jesp.2024.373534
HARVARD
Elfors, M., NAGUIB, A. (2024). 'VONOPRAZAN VERSUS PROTON PUMP INHIBITORS IN COMBINATION WITH ANTIBIOTICS AS A TRIPLE THERAPY FOR ERADICATION OF CLARITHROMYCIN RESISTANT STRAIN OF HELICOBACTER PYLORI', Journal of the Egyptian Society of Parasitology, 54(2), pp. 313-318. doi: 10.21608/jesp.2024.373534
VANCOUVER
Elfors, M., NAGUIB, A. VONOPRAZAN VERSUS PROTON PUMP INHIBITORS IN COMBINATION WITH ANTIBIOTICS AS A TRIPLE THERAPY FOR ERADICATION OF CLARITHROMYCIN RESISTANT STRAIN OF HELICOBACTER PYLORI. Journal of the Egyptian Society of Parasitology, 2024; 54(2): 313-318. doi: 10.21608/jesp.2024.373534