TOXOPLASMOSIS IN VACCINATED COVID-19 PATIENTS

Authors

1 Department of Clinical and Molecular Parasitology

2 Department of Clinical Pathology

3 Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Menoufia Governorate, Egypt

Abstract

Toxoplasma gondii is associated with viral infections like cytomegalovirus (CMV), and human
immunodeficiency virus (HIV), and an important a factor in SARS-COV-2 global pandemic.
This study investigated the potential attribution of T. gondii as a risk factor in COVID-19 infection
after vaccination and to detect associated hematological and biochemical parameters.
Out of 375 COVID-19 patients enrolled in the study, latent toxoplasmosis was detected in
108/375 (28.8%) patients. Regarding hematological parameters, a significant difference was reported
in white blood cells, lymphocyte, and neutrophil counts. Biochemical parameters, LDH
(426.5±446.4), ferritin (453.71±283.36), and D-dimer (603.43±519.13) were significant among
cases. The current work highlights the role of toxoplasmosis in COVID infections following
vaccination through the changes in the hematological and biochemical parameters

Keywords