Blastocystis is an opportunistic parasite causes gastro-intestinal symptoms including irritable bowel syndrome (IBS). This study evaluated the effect of probiotics and silver nanoparticles on Blastocystis hominis in mice and compared between both probiotics (Lactobacillus) and silver nanoparticles as compared to metronidazole. A cross-sectional study was done in which stool samples were collected from patients suffering from IBS.The stool samples were examined microscopically to detect B. hominis and any co-parasitism. All positive stool samples were cultured on Modified Jones' media. BALB/C mice were infected by isolated Blastocystis. The effect of probiotics and silver nanoparticles on blastocystosis was tested in experimentally infected mice. Cysts' mean count in stool of infected mice markedly decreased; with a decrease in serum levels of nitric oxide and glutathione antioxidants compared to drug control one. There was intestinal villi improvement of infected groups treated with probiotics and silver nanoparticles,with mild inflammation and decrease of Blastocystis at the intestinal surface as compared to the infected group metronidazole treated.
EL-ASKARY, H. M., M. ISMAIL, M. A., ABU-SAREA, E. Y., FAROUK, E. M., EL-WAKIL, E. S., EL-BADRY, M. A., RAAFAT, A., AHMED, M. M., & IBRAHIM, S. S. (2021). SILVER NANOPARTICLES AS APROMISING TREATMENT FOR BLASTOCYSTIS HOMINIS IN EXPERIMENTALLY INFECTED MICE. Journal of the Egyptian Society of Parasitology, 51(2), 343-354. doi: 10.21608/jesp.2021.193314
MLA
HALA M. EL-ASKARY; MOUSA A. M. ISMAIL; ENAS Y. ABU-SAREA; EMAN M. FAROUK; EMAN SAYED EL-WAKIL; MOHAMED A. EL-BADRY; AMIRA RAAFAT; MARWA M. AHMED; SHIMAA S. IBRAHIM. "SILVER NANOPARTICLES AS APROMISING TREATMENT FOR BLASTOCYSTIS HOMINIS IN EXPERIMENTALLY INFECTED MICE". Journal of the Egyptian Society of Parasitology, 51, 2, 2021, 343-354. doi: 10.21608/jesp.2021.193314
HARVARD
EL-ASKARY, H. M., M. ISMAIL, M. A., ABU-SAREA, E. Y., FAROUK, E. M., EL-WAKIL, E. S., EL-BADRY, M. A., RAAFAT, A., AHMED, M. M., IBRAHIM, S. S. (2021). 'SILVER NANOPARTICLES AS APROMISING TREATMENT FOR BLASTOCYSTIS HOMINIS IN EXPERIMENTALLY INFECTED MICE', Journal of the Egyptian Society of Parasitology, 51(2), pp. 343-354. doi: 10.21608/jesp.2021.193314
VANCOUVER
EL-ASKARY, H. M., M. ISMAIL, M. A., ABU-SAREA, E. Y., FAROUK, E. M., EL-WAKIL, E. S., EL-BADRY, M. A., RAAFAT, A., AHMED, M. M., IBRAHIM, S. S. SILVER NANOPARTICLES AS APROMISING TREATMENT FOR BLASTOCYSTIS HOMINIS IN EXPERIMENTALLY INFECTED MICE. Journal of the Egyptian Society of Parasitology, 2021; 51(2): 343-354. doi: 10.21608/jesp.2021.193314
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