VIABILITY OF HEPATIC HYDATID CYSTS IN RELATION TO THEIR PARASITOLOGICAL, MICROBIOLOGICAL AND RADIOLOGICAL FEATURES IN PATIENTS TREATED BY DIFFERENT PROTOCOLS

Document Type : Original Article

Authors

1 Department of Medical Parasitology, Faculties of Medicine, Cairo University and Armed Forces College of Medicine, Cairo

2 Department of Pathology, National Research Institute

3 Department of Tropical Medicine, National Hepatology and Tropical Medicine Research Institute

4 Department of Community Medicine, National Research Centre

5 Biomedical Sciences (BSc), University of Manchester, UK

6 Department of Medical Microbiology, Faculty of Medicine, Cairo University

Abstract

Hydatid cyst disease is a parasitic infection caused by larval stage of Echinococcus granulosus
affecting mainly the liver. Diagnosis of hepatic hydatidosis depends on clinical presentations, serological
assays and radiological findings. The present study included 40 patients suffered from
hepatic hydatid cysts. They were classified into 4 groups according to therapeutic protocols they
received. All cases were subjected to serological assay, radiological examination to categorize
cysts and open surgical intervention for treatment. Samples of hydatid fluid and cysts were examined
regarding parasitological, morphometric and histopathological aspects. Viability of cyst
contents was assessed using eosin stain. All samples were cultivated for microbiological assessment.
Viability was 95-100% in GI (no previous treatment), 50-85% in GII, 25-45% in GIII
(single PAIR technique and single Albendazole course) and 0-10% in GIV (repeated PAIR and
medical treatment). Enterococci and Staphylococcus aureus were detected in one sample
in GI and 8 samples in GIV respectively.

Keywords

Journal of the Egyptian Society of Parasitology
Volume 51, Issue 2
August 2021
Pages 313-322

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