2024-03-29T00:20:49Z
https://jesp.journals.ekb.eg/?_action=export&rf=summon&issue=17324
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
CONTROL OF HUMAN FILARIAL VECTOR, CULEX QUINQUEFASCIATUS (DIPTERA: CULICIDAE) THROUGH COMBINATION OF THE ENTOMOPATHOGENIC FUNGUS, METARHIZIUM ANISOPLIAE AND NANOPARTICLES OF ZINC OXIDE AND ALUMINUM OXIDE
SALWA
S. RASHED
GARY
W. BEALL
EMAN
M. RASHAD
WAGEHA
A. MOSTAFA
Culex quinquefasciatus (Diptera: Culicidae) is a vector of many pathogens and parasites of humans,as well as domestic and wild animals. Its eradication or control is regarded as one of the important alternativeavailable in preventing and controlling such diseases. Thus, there is an urgent need to checkthe proliferation of the population of vector mosquitoes in order to reduce vector-borne diseases byappropriate control methods. This study investigated the effect of the entomopathogenic fungus, Metarhiziumanisopliae against Cx. quinquefasciatus larvae, as well as its effect when combined withzinc oxide (ZnO) and aluminum oxide (Al2O3) nanoparticles (NPs). Larvae were exposed to differentconcentrations of fungus, M. anisopliae (1.42×105, 1.42×106, 1.42×107, 1.42×108 spore/ml). Mortalityrates of fourth instars ranged from 100% for the highest spore concentration to 80% for lowest sporeconcentration tested. Larvae exposed to different concentrations of ZnO & Al2O3 (5, 10, & 30mg/ l)combined individually with low concentration of fungus, M. anisopliae, showed significantly highrates of mortality reaching 100% and 96.25% for ZnO & Al2O3, respectively after 4 days of treatment.SEM micrographs confirmed the attachment and penetration of the fungus M. anisopliae into the larvalcuticle in different body parts. The combination of NPs and fungus had a synergistic effect on larvaemortality. This study showed that addition of the synthesized nano-metal oxides to M. anisopliae havegreater efficacy on control of Cx. quinquefasciatus larvae.
Culex quinquefasciatus
Entomopathogenic fungi
Metarhizium anisopliae
Nanoparticle metal oxides
combination effect
2020
08
01
221
227
https://jesp.journals.ekb.eg/article_112999_a91059e1a3d65553786bd8f823a0b1ed.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
ORAL LOSARTAN IN THE PREVENTION OF POST-ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY PANCREATITIS
YASMINE
M. MASSOUD
DOAA
Z. ZAKY
SHEREEN
A. SALEH
RAMY
M. SALEM
HOSSAM
E. SALEM
Generally speaking, acute pancreatitis is a dreadful complication of the endoscopic retro-gradecholangio-pancreatography (ERCP). But, losartan was suggested to prevent the post-ERCP acutepancreatitis. Thus, this study evaluated the use of oral losartan in prevention of the post-ERCPpancreatitis. The study was conducted on 50 patients who received 50mg of oral losartan onehour before ERCP (Study group), and another 50 patients who underwent ERCP without losartanprophylaxis (Control group). Serum amylase and lipase were measured before and after ERCP.The results showed that two patients of the study group and one patient of the control one developedpost ERCP-pancreatitis in a total percent of 3%. The use of oral Losartan in a dose of 50mgan hour before the ERCP did not significantly decrease the incidence of pancreatitis. The ERCPduration was significantly longer among cases that developed pancreatitis in the study group.
Egypt
patients
Losartan
ARBs
ERCP
pancreatitis
2020
08
01
228
234
https://jesp.journals.ekb.eg/article_113001_2ea651723764e5abe4ca9b31683e42c9.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
THE LIGHT MICROSCOPY AND ULTRASTRUCTURAL CHARACTERISTICS OF SARCOCYSTIS FUSIFORMIS INFECTING BUFFALOES IN IRAQ
NAKSHEEN
M. ARDALAN
Samples from fresh muscles of 2-12 years old buffalo (Bubalus bubalis) from Al-Shuala,Baghdad were examined for Sarcocystis infection. Macroscopic ovoid Sarcocystisembedded in the muscle tissues of the examined buffalo were detected, they measured 150-223 (209+7) μm length and 35-130 (85+3) μm width. Esophagus was the highly infectedorgan followed by diaphragm, tongue while the heart muscles were the lowest infected part.The cyst cavity was compartmentalized by septa derived from the ground substance locatedunder the primary cyst wall. By TEM, the primary cyst wall bordered sarcocysts, 0.08-0.22μm in thickness, raised from the parasitophorous vacuolar membrane and surrounded by asecondary cyst wall of host origin. The primary cyst wall had irregular wall folds withnumerous cauliflower projections of variable size and shape accompanied with a knob-likeelectron dense elevation. The interior of the cyst contained merozoites consisted of thestructural elements of the Apicomplexa, polar rings, micronemes, conoid and rhoptries.
Bubalus bubalis
Sarcocystis fusiformis
light and electron microscopy
2020
08
01
235
241
https://jesp.journals.ekb.eg/article_113002_e74a68a286d0440905595ce78872f9fe.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
GIARDIASIS, HELICOBACTER PYLORI AND SERUM LEVELS OF SOME MICRONUTRIENTS
ENAS
Y. ABU-SAREA
RAGHADA
R. FAROUK
MOUSA
A. M. ISMAEL
MOSTAFA
S. SHEEMY
DOAA
M. AHMED
SHAIMAA
A SENOSY
MARWA
A. GHIETH
Giardiasis and H. pylori in upper gastrointestinal system absorbed some vitamins and mineraloccurs. This study detected the serum levels of copper, zinc, vitamins B12 & B9 among giardiasisand/or H. pylori patients and compared the serum levels of these minerals and vitaminsamong them. A total of 95 patients suffered from acute diarrhea were subjected to questionnairetaking, stool analysis, iron/haematoxylin staining, H.pylori antigen detection and serum leveldetection of zinc, copper, vitamins B12 & B9. Patients were divided into G1 (n=13) for microscopicGiardia +ve, G2 (n=40) H. pylori +ve, G3 (n=6) both Giardia & H.pylori +ve, G4(n=36) Giardia & H. pylori –ve (control). The mean age of patients was 45.7±17. On comparingvariables among patients; residence, abdominal pain and flatulence were statistically significant(P ≤ 0.05). Serum levels of zinc, vitamins B12 & B9 were within normal ranges, exceptcopper level was higher than normal in all groups. G3 (co-infections) showed the lowest levelsof zinc, vitamins B12 & B9. None of serum levels were statistically significant on comparingthe four groups. Both giardiasis and H. pylori altered levels of micronutrients but during acuteinfection serum levels of zinc, vitamin B12 & B9 were still within normal ranges. Pattern of infectioneither chronic or acute were basic regarding micronutrients levels.
patients
Giardiasis
H. pylori
copper
zinc
Vitamins B12
& B9
2020
08
01
242
246
https://jesp.journals.ekb.eg/article_113038_1445c4800e99e550c7f10926b880749a.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
A MINI-OVERVIEW OF VITAMIN E
TOSSON
A. MORSY
ABDULLAH
D. ALANAZI
Vitamin E (tocopherol) is a fat-soluble vitamin with antioxidant properties; it protects cellmembranes from oxidation and destruction, found in a variety of foods including oils, meat,eggs, and leafy vegetables. Their serums levels are strongly influenced by concentration of serumlipids, and do not accurately reflect tissue vitamin levels. Effective vitamin E levels arecalculated as the ratio of serum alpha-tocopherol per gram total lipids.Absorption of dietary vitamin E requires effective pancreatic exocrine function and fat absorption,unless provided in a synthetic water-soluble form. Also, a specific protein (alphatocopheroltransfer protein) is required for effective transport and use. Signs and symptoms ofvitamin E deficiency include hemolysis, neuromuscular disorders, ataxia, and peripheral neuropathy.Because of an abundance of tocopherols in the human diet, its deficiency is rare exceptin individuals with pancreatic insufficiency or other conditions causing substantial fat malabsorption,or protein-energy malnutrition and may be caused by rare genetic defects affectingvitamin E metabolism or transport. No syndrome of acute vitamin E toxicity has been described.In premature infants, high-dose vitamin E treatment was associated with increased riskfor sepsis. Chronic intake of supplements in excess of 400 IU daily has been associated with increasedrisk of hemorrhage and all-cause mortality.
Vitamin E
Action
requirements
Deficiency
toxicity
Therapeutic role
2020
08
01
247
257
https://jesp.journals.ekb.eg/article_113040_a199be2e8d260b6dce8662d5196f2cee.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
RELATION OF LACTOBACILLI ACIDOPHILUS TO OBESITY IN EGYPTIAN POPULATION
RASHA SAMIR
MOHAMED
MAHA ABDELAZIZ AHMED
ELTOUNY
GEORGE SAFWAT
RIAD
HANY NASER ABBAS
HANY
Current considerations are existed about the sharing role of gut microbiota in the enhancementof obesity and allied comorbidities. This observational case-control study assessed the possiblerelation of Lactobacilli acidophilus to obesity in a sample of Egyptian population by real-timePCR in stool. The study enrolled 20 healthy slim subjects and 40 subjects who had BMI >25kg/m2. Routine laboratory analysis and identification of stool L. acidophilus by quantitative realtime PCR technique was performed for all enrolled subjects. Lactobacillus acidophilus was expressedin 21/40 (52.5%) fecal samples of obese cases and 16/20 (80%) of fecal samples of nonobeseones. In rest of samples in both groups, the expression was below the detection limit. Theresults showed that the mean lactobacilli CT was expressed in obese cases (38.89±2.57) comparedto (36.08±4.63) in non-obese cases, with high significant difference (P =0.04). Lactobacillusacidophilus was significantly lowered in obese Egyptian patients. The argument aboutsignificance correlation between imbalance in gut microbiota and obesity is one of the hot topicsin medicine.
Obesity
Gut Dysbiosis
Lactobacilli acidophilus
2020
08
01
258
264
https://jesp.journals.ekb.eg/article_113043_39c9f6aebf59e0b19855651cede3b7eb.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
MAY SCHISTOSOMIASIS HAEMATOBIUM AND MANSONI LEAD TO INFERTILITY IN THE HOST?
HEBA ABDEL KADER
AMINOU
AYMAN
IBRAHIM
Schistosomiasis is worldwide water-borne infectious risky disease. Steroid hormones are synthesizedfrom cholesterol in adrenal glands and gonads. They include corticosteroids, androgens,estrogens and progestogens. The present study evaluated the effect of Schistosoma mansoni andS. haematobium infections on the hamsters’ fertility as indicated by the changes of steroid sexhormones levels. Eighteen Mesocricetus auratus clear laboratory bred hamsters (9 males & 9females) were divided into 3 groups. G1: was infected with S. mansoni cercariae, G2: was infectedwith S. haematobium cercariae, and G3: was not infected (negative control). The resultsshowed that testosterone level increased in all infected hamsters but markedly increased in thoseinfected with schistosomiasis haematobium (7.52 & 0.78nmol/L) as compared to control (2.41 &0.341nmol/L). Progesterone level decreased in all infected hamsters especially in S. mansoni andS. haematobium females (5.732 & 11.13nmol/L) in comparison to control (86.34 &64.7nmol/L). Estradiol E2 level markedly decreased in female hamsters infected with either S.mansoni or S. haematobium (247.54 & 463.8pmol/L) as compared to control (1658pmol/L) butnot detected in male hamsters.
Schistosoma species
Hamsters
testosterone
estradiol
progesterone
Infertility
2020
08
01
265
269
https://jesp.journals.ekb.eg/article_113046_133132d8283bae4fee45a6e3ce45413d.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
JELLYFISH STINGS: COMPLICATIONS AND MANAGEMENT
TOSSON A.
MORSY
NAHLA M.
SHOUKRY
MAHMOUD A.
FOUAD
Jellyfish and sea jellies are the informal common names given to the medusa-phase of certaingelatinous members of subphylum Medusozoa, the majority of phylum Cnidaria. Jellyfish aremainly free-swimming marine animals with umbrella-shaped bells and trailing tentacles, althougha few are not mobile, being anchored to the seabed by stalks. The bell can pulsate to givepropulsion and highly efficient locomotion. Tentacles are armed with stinging cells and may beused to capture prey and defend against predators. Jellyfish have a complex life cycle; the medusais normally the sexual phase, the planula larva can disperse widely and is followed by a sedentarypolyp phase.Jellyfish are found worldwide, from surface waters to the deep sea. Scyphozoans ("true jellyfish")are exclusively marine, but some hydrozoans with a similar appearance live in freshwater.Large, often colorful, jellyfish are common in coastal zones worldwide. The medusae of mostspecies are fast growing, mature within a few months and die soon after breeding, but the polyp < br />stage, attached to the seabed, may be much more long-lived. Jellyfish have been in existence forat least 500 million years, and possibly 700 million years or more, making them the oldest multiorgananimal group. They are eaten by humans in certain cultures, being considered a delicacyin some Asian countries, where species in the Rhizostomae order are pressed and salted to removeexcess water. They are also used in research, where the green fluorescent protein, used bysome species to cause bioluminescence, has been adapted as a fluorescent marker for genes insertedinto other cells or organisms. Stinging cells used by jellyfish to subdue their prey can alsoinjure them. Many thousands of swimmers are stung every year, with effects ranging from milddiscomfort to serious injury or even death; small box jellyfish are responsible for many deaths.
jellyfish
Zoonotic importance
Management
Recommendation
Review
2020
08
01
270
280
https://jesp.journals.ekb.eg/article_113048_8223eb9201d241bd84a17275b89b97e5.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
A STUDY OF IMMUNOTHERAPEUTIC EFFICACY OF TRICHINELLA SPIRALIS EXCRETORY-SECRETORY PROTEINS IN MURINE TRICHINELLOSIS
TAHANY
AL-ATTAR
WAFAA
EL-KERSH
GEHAN
SADEK
NANCY
HARBA
SALWA
OSHEIBA
REHAM
BRAKAT
Trichinellosis is a serious zoonotic parasitic and globally endemic disease. Benzimidazole derivativesare apparently unable to kill encapsulated larvae and its effectiveness depends on solubility, dosage oftherapy, host biotransformation, selectivity patterns as well as onset of treatment after infection. Excretory-secretory (ES) proteins released by Trichinella induce a strong immune response when tested as avaccine. The current study investigated both therapeutic and protective effects of adult worm excretorysecretory protein (AW/ES), or larval excretory secretory protein (LES) on T. spiralis infected mice,conducted by parasitological, histopathological, immunohistochemical, serological and molecular investigations.Larval excretory secretory protein achieved more significant therapeutic and protectiveeffects than adult worm excretory secretory protein in experimentally infected mice, causing reductionin larval counts and decrease in pathological changes of both muscular and intestinal tissues. It increasedserum IgG OD values, decreased Foxp3 expressions and increased the mean cycle thres- holdvalues of muscular tissues but it had lesser effects on adult worm counts than albendazole.
Mice
Trichinella spiralis
Immunotherapeutic efficacy
Excretory-secretory proteins
2020
08
01
281
292
https://jesp.journals.ekb.eg/article_113049_e764908ea1479505c8fccc9d72f168da.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
EFFICACY OF AZITHROMYCIN ON EXPERIMENTAL TOXOPLASMOSIS INFECTED MICE
MONA E.
NASR
ATEF H.
ABD EL HAMID
NAGWA S. M.
ALY
GHADA H.
OMAR
ASHRAF M. A.
BARAKAT
KAWKAB A.
AHMED
SAFAA H.
YOUSSIF
GEHAN A.
RASHED
Toxoplasma gondii is an opportunistic protozoan that causes a devastating disease in immunocompromisedindividuals and congenitally infected neonates or children. This study evaluated theefficacy of early Azithromycin treatment of Toxoplasma gondii infected mice with cystogenic Me49 non-virulent strain. Fifty laboratory-bred female Swiss albino mice were divided into 5 groups:G1: Non-Infected, G2: Infected non-treated, G3: Infected and treated by Azithromycin 200mg/kg at 4th day post-infection for 3 days, G4: Infected and treated by Azithromycin 200mg/kg at4th day post-infection for 10 days & G5: Infected and treated by Spiramycin 200mg\kg at 4th daypost-infection for 2 weeks, brain cysts’ number, size and histopaholoical changes were assessedafter 3 months. Treatment with Azithromycin for 10 days decreased number and size of braincysts by 70% & 40% respectively without significant difference with Spiramycin treated micethat caused reduction by 74% & 50% respectively. Azithromycin treatment for 3 days caused theleast reduction by 51% & 21% respectively and Azithromycin treatment for 10 days decreasedthe histo-pathological changes in cerebral toxoplasmosis. Azithromycin treatment started at 4thday post-infection was effective than Spiramycin against T. gondii infection with a significant effecton cysts count and size and brain pathological changes. Azithromycin treatment for 10 daysgave better effect than 3 days.
Mice
Azithromycin
Spiramycin
toxoplasma gondii
Treatment
2020
08
01
293
299
https://jesp.journals.ekb.eg/article_113050_f9199af8232f928223754daeee292a34.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
CAN HUMAN TOXOPLASMOSIS BE WITHIN THE DIFFERENTIAL DIAGNOSIS OF FEVER OF UNKNOWN ORIGIN: A CROSS-SECTIONAL STUDY
AHMED M.
ARNOUS
NAHLA E.
ELGAMMAL
NAHED E.
MOSTAFA
EMAN M.
FAWZY
MARWA A.
SALAMA
More than 200 diseases can be represented in differential diagnosis of fever of unknown origin(FUO). The mainstay for the proper diagnosis of FUO took right path for the correct investigations.Globally, Toxoplasma gondii infection persists lifelong within the affected host organs inthe dormant bradyzoites form. Once the host immunity decreases, it can be converted back tothe activate tachyzoite form that attach the host cells. The aim of our study is to estimate thefrequency of toxoplasmosis in patients with fever of unknown origin, concerning the etiology.A cross-sectional study was done from November 2017 to May 2018, including 140 patientschosen with FUO (100 males &40 females), recruited from Port Said Fever Hospital/ Egypt.Their ages ranged between 16 and 70 years old. Patients were subjected to comprehensive historytaking, laboratory investigations, clinical and radiologic examination. Detection of anti-Toxoplasma IgM&IgG antibodies was done by the Electrochemiluminescence immunoassay.Patients had fever with known origin proved by investigations, were excluded from the study.The results showed that 7.1% of the FUO cases were serologically positive for ToxoplasmaIgG. Of them, 80% were females and 20% were males. About 70% of Toxopl-asma-IgG positivecases were represented with fever for 3weeks, and 30% were represented with fever formore than 3weeks. The 70% of the target group had cervical lymphadenopathy and all of themhad hepatosplenomegaly. Moreover, all cases were eating fast food.
patients
Fever of unknown origin Toxoplasmosis
lymphadenopathy
2020
08
01
300
306
https://jesp.journals.ekb.eg/article_113051_ec8f5c3311856616a080f783bbaa0e10.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
ANTIPARASITIC ACTIVITY OF MYRRH CRUDE EXTRACT AND MYRRH VOLATILE OIL COMPARED TO ALBENDAZOLE AGAINST TRICHINELLA SPIRALIS MUSCULAR LARVAE IN VITRO
SALWA M.
ABD-ELRAHMAN
AHMED K.
DYAB
ABEER E.
MAHMOUD
SHYMAA M.
MOSTAFA
NAHED A.
ELOSSILY
Trichinellosis is a foodborne zoonotic disease caused by T. spiralis affecting human and animals.Treatment with commercially available drugs has not been satisfactory due to rapid developmentof drug-resistant particularly against encapsulated larvae. There is an increasingneed to discover alternative anthelminthics agents from medicinal plants. The present studyevaluated the in vitro antiparasitic activities of myrrh crude extract and myrrh volatile oil on T.spiralis larvae compared to albendazole to estimate their sublethal concentrations on the infectivityof T. spiralis larvae in mice. The in vitro effect of these agents was evaluated by assessingmortality rate and by a scanning electron microscopic analysis of ultrastructural changes inthe cuticle of the larvae. The surface changes induced by crude myrrh extract and albendazolewere more severe than those observed after exposure to myrrh volatile oil. All responses to thesubstances were time dose-dependent and highly significantly different from the control group < br />(p < 0.001). 100% mortality rate of larvae occurred on the 4th day at 3, 5, &7mg/ml of myrrh crudeextract, on the 7th day with volatile oil while total larval death occurred on the 1st day of exposurein to 5, 10, 15 & 20μg/ml of albendazole. In vitro exposure to sublethal dose of albendazole,crude myrrh extract and volatile oil extract resulted in infectivity reduction by 100%, 98%& 88% respectively in intestinal phase and 100%, 98% &59% respectively in muscular phase.
in Vitro
Trichinella spiralis
albendazole
Myrrh crude
Myrrh volatile oil
2020
08
01
307
314
https://jesp.journals.ekb.eg/article_113052_5aaf3598e64eeb698e2103577e035c4b.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
MYOSTATIN LEVEL IN CRF PATIENTS WITH AND WITHOUT POST-HCV CIRRHOSIS AND ITS CORRELATION WITH BMI
MOHAMED
SALAMA
MOHAMED
MAKHLOUF
HAGAR
ELESSAWY
MOHAMED
EL BADRY
HEBA
ELFOULY
Chronic kidney disease (CKD) is a progressive condition that may negatively affect musculoskeletalhealth. Secondary sarcopenia due to CKD may be associated with mobility limitationsand elevated fall risk. Thus, it is important to investigate surrogate methods that enablethe assessment of muscle mass. Myostatin regulates synthesis and degradation of skeletal muscleproteins and is associated with the development of sarcopenia. This study assessed the myostatinlevel in CKD patients and correlated with body mass index. This a prospective casecontrol study, carried out on 30 Egyptian patients with CKD (15 have post-HCV cirrhosis) attendedfor dialysis in Al-Hammoul Central Hospital and 15 healthy controls. All patients weresubjected to detailed medical history and through clinical examination, abdominal ultrasoundand determination of serum myostatin level. The mean, standard deviation and chi-square werecalculated by SPSS. ROC curves were conducted to test the discriminative value of myostatinlevel on sarcopenia and to detect the cut-off points. The results showed significant increase inthe serum myostatin level in hemodialysis patients. Myostatin level in post-HCV cirrhotic patientswas insignificantly higher than in non-cirrhotic patients. There was a significant negativecorrelation between serum myostatin level and BMI and skeletal muscle index (SMI). ROCcurve showed that a cut off value of 39.05ng/ml can detect sarcopenia in hemodialysis patients.
Chronic renal disease
Myostatin
HCV
BMI
Cirrhosis
2020
08
01
315
321
https://jesp.journals.ekb.eg/article_113053_14c6d2f2d3a7f959debb55cc71f3cd6a.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
TOXICOLOGICAL AND BIOLOGICAL INDICES OF THE HOUSE FLY, MUSCA DOMESTICA AFTER CSI'S TREATMENTS: LUFENURON, FLUFENOXURON AND HEXAFLUMURON
ENAS E.
NASR
SHADY
SELIM
MUHAMMAD A.
TANANI
The house fly, Musca domestica transmits many diseases to humans, so that controlling it withoutside effects on human health is extremely important. Therefore, the current study aimed tocompare the toxicity of tested chitin synthesis inhibitors (CSIs) lufenuron, flufenoxron, and hexflumuronagainst 3rd instar larvae of the house fly, and to assess the lethality effects by serialconcentrations (1000, 500, 250 & 125ppm) of each tested compound on the developmental parametersand growth indices of the immature stages of M. domestica. The least toxicity valuesof sub-lethal concentrations (LC25, LC50 & LC75) displayed for lufenuron (158.23, 332.46 &698.56, respectively). Also, hexaflumuron scored (64.06ppm at LC25), followed by flufenoxuron(140.95 & 283.62ppm at LC50 & LC75, respectively). Flufenoxuron was the most toxic, followedby hexaflumuron and lufenuron. CSIs showed a toxic efficiency on 3rd instar larvae of M. domesticaby decreasing developmental and growth indices rates at higher concentrations of eachone. Flufenoxuron exhibited a marked significant decrease in larval development and growth indexrates (15.50 & 2.71% at 1000ppm, respectively), highest water loss (69.79%) compared tohexaflumuron and lufenuron. Flufenoxuron was the most toxic one against pupae as compared toothers, it prolonged pupal duration (14.71day) and induced pupal water loss (53.77%), its pupation,developmental and weight rate reduced (17.5 & 6.8%, & 53.77mg respectively). But, growthindex did not cause mortality with the highest concentration. Adult emergence displayednon-adult emergence and a high percentage of the malformation rate at 1000ppm when treatedwith flufenoxuron compared to other compounds.
M. domestica
lufenuron
Flufenoxuron
Hexaflumuron
larvicidal
pupation
develop ment
Growth
2020
08
01
322
332
https://jesp.journals.ekb.eg/article_113054_6a6713a930ed2b05f9b5d5bf770d8d00.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
ANXIETY AND ITS ASSOCIATED FACTORS AMONG OLDER PATIENTS UNDERGOING CORONARY ANGIOGRAPHY AND PERCUTANEOUS CORONARY INTERVENTION
EMAN SHOKRY
ABD ALLAH
SHERIHAN
ALI
HASSANAT RAMADAN
ABDEL-AZIZ
Coronary Angiography and Percutaneous Coronary Interventions (PCI) are diagnostic andtherapeutic procedures often for patients with CAD. Although these are minimally invasive andhave relatively low risk, most patients showed pre-procedural anxiety. The present study assessedthe anxiety level and factors associated with it among older Adults undergoing coronaryangiography and percutaneous coronary intervention. A total of 155 older patients undergoingCoronary Angiography and PCI at Cardiac Catheterization Units, Zagazig University Hospitalswere selected.The results showed that 58.1% of the studied older adults patients had moderate anxiety,while, 25.8% of them had severe anxiety and only 16.1% of them had mild anxiety level. Thehighest rates of anxiety were found in in female patients with age greater than or equivalent to70 years compared with other age groups, with low educational level, had chest pain attack andthose without previously cardiac intervention.
Oder Adults
Anxiety level
Associated-factors
Coronary angiography
Percutaneous coronary interventions
2020
08
01
333
343
https://jesp.journals.ekb.eg/article_113055_37e601b62da527e9d18a265ff6a02936.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
REPURPOSING OF ANTI-MALARIAL SYNRIAMTM AND TESTING ITS EFFICACY AGAINST EGYPTIAN STRAIN OF SCHISTOSOMA HAEMATOBIUM
HEBAT-ALLAH S.A.
YOUSOF
SHAIMAA H.
EL-SAYED
EMAN
ELFAR
MONA M.
KHATER
Trials for discovering an anti-malarial drug, which can compete Schistosomal infection inco-endemic areas, are ongoing. Some preliminary studies were done on Synriam (SYN), antimalarialdrug combination (arterolane maleate and piperaquine phosphate) released fromRanbaxy, to test its anti-schistosomal effect. But, in vitro incubation of SYN with differentSchistosoma haematobium stages was not fully assessed. This study determined the antischistosomalin vitro effect of SYN on adult and juvenile stages of Schistosoma haematobium-Egyptian strain. Adult and juvenile worms were incubated with ascending concentrations ofSYN and with praziquantel as positive control. Viability, survival, morphological and ultrastructuralchanges were assessed at different time points. Higher concentrations of 60, 80μg/ml showed rapid and lethal effects on adult and juvenile stages of both species, with prominentultrastructural alterations. Concentrations of (10, 20, & 40μg/ml) showed mild to moderateeffect on adult schistosomes. On contrarily to praziquantel, larval immature stages respondedsignificantly and rapidly to low concentration of SYN with 100% death rate. The presentfindings were consistent with the evaluation of anti-schistosomal therapeutic effect of SYN tobe utilized in malaria co-endemic areas.
Anti-schistosomal, In-vitro
Schistosoma haematobium
Schistosoma mansoni
Synriam
Drug repurposing
2020
08
01
344
352
https://jesp.journals.ekb.eg/article_113056_ec44a8c39df455a3334d59661fa35367.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
ANTHELMINTHIC EFFECT OF TAMOXIFEN ON EXPERIMENTALLY HYMENOLEPIS NANA INFECTED MICE
AMANY F.EL
FAKAHANY
MOHAMED H. S.
IBRAHIM
ATEF H.
HUSSEIN
NAGLAA A. M.
EL SAWY
HEMAT S. M.
ALI
Hymenolepis nana is one of the commonest parasites worldwide especially in children. Praziquantelwas the most effective drug in hymenolepiasis treatment, but with the risk of resistancedevelopment. There was a need for search for drug(s) to overcome this problem. Tamoxifen(an estrogen-receptor modulator), is available, low cost with potential anti-parasitic efficacy.This study assessed the therapeutic effect of tamoxifen drug on mice experimentally infectedmice with H. nana at different developmental stages. Clean laboratory bred mice infected withH. nana eggs were divided into 4 groups according to different schedule of tamoxifen administration(20mg/kg body weight) at the parasite different developmental stages and control one(infected non treated). At the experimental mice were sacrificed and parasitological evaluatedfor worm burden count, their weight, egg count and viability. The results did not show statisticallysignificant effect on worm burden as compared to control one, with the exception of micetreated two days post-infection that showed significant increase in worm burden. There wassignificant decrease in worm weight, egg count and viability as compared to control ones, butwithout difference between different treated groups.
Mice
Hymenolepis nana
Tamoxifen®
Parasitological evaluation
2020
08
01
353
357
https://jesp.journals.ekb.eg/article_113057_382d37dc082981df18f75239365aeb0a.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
MAPPING OF SCHISTOSOMA HEAMATOBIUM IN QENA DISTRICT, QENA GOVERNORATE, UPPER EGYPT; HOSPITAL-BASED STUDY
ASMAA M.
EL-KADY
AHMED M.
SEFELNASR
DOAA MM.
OSMAN
MARWA K.
KHAIRALLAH
AMR H.
ABOU FADDAN
MONA M.
GABER
Schistosoma haematobium infection is one of the most serious endemic parasites worldwideespecially Africa. In Egypt, in spite of the control massive advances in reducing country-wideschistosomiasis prevalence rates; yet, endemic foci still exist. This study determined the percentageof positive urinary schistosomiasis cases among patients who complained from hematuriaand or dysuria at Qena General Hospital and to conduct a spatial mapping of S. haematobium infectionin Qena Governorate, Egypt.A cross-sectional study was conducted at the Urology and Nephrology outpatient clinics atQena General Hospital from January 2016 to December 2018. The subjects were permanent residentsin Qena district who complained of either hematuria and/or dysuria (N= 2371). The urinesamples were subjected to full parasitological examinations. A detailed personal history was obtainedafter informed consent from them.The results showed that 568/2371 (24%) cases were positive for Schistosoma haematobium.The largest number of positive cases were recorded in autumn (44%) followed by winter(35.2%). Significantly higher odds ratios were among young male patients (less than 18 years)presented complaint in seasons other than summer, and lived in villages in the western bank ofthe River Nile. But apparently, higher number of infected cases was detected in eastern villagescompared to western ones. Statistical analysis showed that living in the western area in Qenadistrict was a risk factor for S. haematobium infection. It coincides with studying geological criteriaof Qena district where western area is concave shape with slow water flow that allow moreprobability for snails’ existence and consequently higher susceptibility for infection compared toconvex shape of the eastern area.
Schistosoma haematobium
Qena District
hematuria
Dysuria
Spatial Pattern
2020
08
01
358
363
https://jesp.journals.ekb.eg/article_113058_4d863594c6c9d3255ec6896b28161cc5.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
MALE PARTNER INVOLVEMENT IN PREVENTION OF MOTHER TO CHILD TRANSMISSION OF HIV AT KIBAHA TOWN, TANZANIA
NARGIS
LABIB
MOHAMED
EL-AWADY
GOODLUCK
MARO
AMR
ELSYAYED
Male partners must be considered as part of prevention of mother to child transmission(PMTCT) of HIV, because they often make key decisions which affect health of women andtheir children. Study objectives: To measure the percentage and level of male partner involvementin PMTCT. To identify some factors affecting male partners’ involvement. Methods: Itwas hospital based cross sectional study, done at Tumbi referral Hospital, Kibaha regionalhealth centre and Royal private hospital, at Kibaha Town Tanzania.107 HIV positive postnatalmothers, their male partners and their infants were included in the study. Questionnaire wasused for data collection and it has three sections: section I: Male partners, section II: Femalepartners and section III: Infants born from HIV positive mothers. Results: Male partners’ involvementwas, 62%. Their involvement was associated increase utilization of prevention ofmother to child transmission services. Friendly health care workers were the main factor affectingmale partner involvement. Nine percent of infants were HIV positive in Early HIV diagnosistest. Conclusion: It was concluded that male partner’s involvement was associatedwith increased utilization of mother to child transmission services.
male
partners
Involvement
prevention
Mother
Child
Transmission
HIV
2020
08
01
364
369
https://jesp.journals.ekb.eg/article_113059_4cfae6cf0466c496124680a86d403d78.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
TOXOPLASMOSIS AND NEUROLOGICAL DISEASES IN CHILDREN: A SERIOUS RISK OR MERE ASSOCIATION
NOHA M.
AMIN
ALY
ELKAZAZ
IMAN R.
ABDEL-SHAFI
EMAN HANY
ELSEBAEI
MAGDA SAID A.
ABDELTAWAB
Tracing the etiology of paediatric neurological disorders back to toxoplasmosis was often difficultand particularly challenged, depended mainly on serology in common practice. The currentstudy evaluated the role of toxoplasmosis and oxidative stress in Egyptian children sufferingfrom acute neurodevelopmental disorders, by seroprevalence in relation to IFN gamma in patientswith positivity for IgG & IgM. The result showed that out of 155 patients, 128 (82.6%)were positive for IgG and 10 (6.5%) were positive for both IgG & IgM. Also, the serummalondialdehyde (MDA) was significantly higher in seropositive pa-tients than in seronegativeones. Six children suffered from acute toxoplasmosis showed high levels of serum IFN gamma.
Toxoplasmosis
Neurological disorders
seroprevalence
qPCR
MDA
IFN gamma
2020
08
01
370
377
https://jesp.journals.ekb.eg/article_113060_b948e791de2b41412e34f385826f7bfb.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
TISSUE SPARING TECHNIQUE IN LIVER HYDATID DISEASES: THREE-WAY TECHNIQUE VERSUS HYDATID CONE TECHNIQUE
EISSA ABDEL HAMED
IBRAHIM
TOSSON ALY
MORSY
Echinococcosis (known as hydatid disease or hydatidosis) is a serious, sometimes fatal, zoonoticdisease caused by Echinococcus two species. E. granulosus, causes worldwide cystic echinococcosis(hydatidosis) maintained in domestic transmission cycle involving dogs and livestockmainly sheep, and E. multilocularis, causes alveolar echinoccososis endemic in the northern hemispherein wild transmission cycle involving dogs and wild carnivores and rodents. Intermediatehosts including man are infected by ingestion of eggs dropped from dog with food, fluidor fingers, or by crawling insects from site of fecal deposition. Eggs hatch in gut into invasiveoncospheres, which penetrate intestinal mucosa, enter venous and lymphatic pathways. Theseoncospheres according to species developed into unilocular or classical hydatid disease or cysticechinococcosis, with few years’ incubation period or infiltration into alveolar or multilocularechinoccososis with 10-30 years incubation period. The clinical pictures of E. granulosus wereusually from asymptomatic to fatal. But, alveolar echinoccososis particularly in the liver becomesmetastatic and is frequently fatal. Chemotherapies (albendazole, mebendazole or praziquantil)may be of value prior to surgery or in inoperable cases, but alveolar cysts may require bothsurgery and prolonged chemotherapeutic treatment.Liver surgery has gone through the phases of wedge liver resection, regular resection of heapticlobes, irregular and local resection, extracorporeal hepatectomy, hemi-extracorporeal hepatectomyand others. Taking the modern technologies advantage, the liver surgery is stepping intoan age of precise liver resection.
patients
Hydatidosis
Scolicidal agent
Three-way technique
2020
08
01
378
389
https://jesp.journals.ekb.eg/article_113061_b070b787b8e5fbd2cbd0683baf287be9.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
HELICOBACTER PYLORI CO-INFECTED WITH COMMON INTESTINAL PROTOZOA IN GASTROINTESTINAL SYMPTOMATIC PATIENTS
MARWA M. I.
GHALLAB
SALWA M.
MORSY
The zoonotic intestinal protozoan parasites and Helicobacter pylori) are worldwide distributedhuman pathogens. This study evaluated the co-infection between H. pylori and the commonestintestinal protozoan parasites. A total of 240 stool samples were collected over one yearfrom patients attending outpatients' clinics of Kafrelsheikh University Hospitals, after verbalconsent for participation. Samples were subjected to microscopic examination directly beforeand after formol ether concentration. Samples were examined using merthiolate iodine formalin(MIF) direct smears to detect G. intestinelis and permanent modified trichrome and modifiedacid-fast cold kinyoun's stained smears to detect E. histolytica/dispar and Cryptosporidium spp.respectively. Screening with immune-chromatographic test (ICT) detected H. pylori infection.The results showed that H. pylori were in 160/240 (66.7%). Univariate analysis showed significanceassociation between H. pylori and protozoan causing diarrhea (P = 0.015). These protozoanparasites were with G. intestinalis ((P=0.002), E. histolytica/dispar (P= 0.041), Cryptosporidiumparvum (P =0.018) and Blastocystis hominis (P= 0.040).
patients
Heliobacter pylori
Intestinal protozoan parasites
2020
08
01
390
393
https://jesp.journals.ekb.eg/article_113063_70eae5cdfa69c98c9d0a1180f24b8b3e.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
FIRST IMMUNOLOGICAL RECORD OF BABESIA MICROTI HOBET SULINEAGE ANTIBODIES AMONG HUMAN BLOOD DONORS IN QENA GOVERNORATE, UPPER EGYPT, EGYPT
OSAMA H.
ABDELLAH
NOHA SAMMER
AHMED
MOHAMMED H.
HASSAN
ASMAA M.
EL-KADY
The zoonotic babesiosis is a growing public health concern. This parasite mainly occurs in U.S.(B. microti) and Europe (B. divergens & B. venatorum). Emerging cases have been increasinglyreported worldwide especially in immunosuppressed individuals. Other than tick bite, possiblemodes of infection include perinatal transmission and blood transfusion. To date, in Egypt, threecases of human babesiosis were reported. This study evaluated Babesia spp. infection in man inQena City. Forty three persons were examined. All sera were subjected to serological examinationusing either indirect fluorescent antibody test (IFA) or western blot (WB) analysis or bothtests. Using IFA 13/43 patients were positive for Babesia at different titers. The five out of the13 positive IFAT samples were positive by using WB test (11.6%). This could be the first studyin Qena that screened Egyptian patients using well-defined Babesia strain for human babesiosis.Blood transfusion is a possible babesiosis mode of infection to man and thus patients in need ofblood transfusion may undergo immunosuppressive status so they may develop babesiosis, soscreening of blood donors for human babesiosis is needed to exclude transfusion inducedbabesiosis.
Egypt
Blood donors
Babesia microti
Hoetsu
western blot
IFA
2020
08
01
394
400
https://jesp.journals.ekb.eg/article_113065_183d9f2fa2ca2ad9e4b31c355dc9a6a9.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
TRICHINELLA SPIRALIS INFECTION PROTECTS AGAINST OVALBUMININDUCED ALLERGIC BRONCHIAL ASTHMA IN A MURINE MODEL
NORHAN B.
SALLAM
SANAA N.
ANTONIOS
NEMA A.
SOLIMAN
DINA I.
ELGENDY
Allergic bronchial asthma is a long-lasting illness of the respiratory system characterized bychronic inflammation of the respiratory airways with abnormal Th2-type immune responses tospecific allergens. The accumulation of scientific evidence supports the beneficial effects ofsome parasitic infections in animal models of allergic diseases. Thus, the aim of this work wasto discover the influence of infection with T. spiralis on ovalbumin-induced acute allergic airwayinflammation in mice and to investigate whether this effect is correlated to the infectiondose or not. Therefore, the severity of respiratory airways inflammation, the leukocyte counts inthe blood and BALF, immunohistochemistry of FOXP3+CD4+T cells and the levels of IL-6, IL-13, and IL-10 were assessed. In this experiment, 120 male laboratory bred mice were randomlydivided into six groups: induced asthma, saline control, low dose preventive, high dose preventive,low dose therapeutic and high dose therapeutic groups. T. spiralis infection attenuated theintensity of pulmonary inflammation, decreased numbers of eosinophils in BALF and blood,reduced levels of IL-6 and IL-13 and elevated levels of IL-10 with a significant upregulation ofFOXP3+CD4+T cells expression compared to the uninfected induced asthma group. The preventivegroups showed the best results with no significant difference between effects of the low andthe high doses. In conclusion, T. spiralis infection reduced Th2 type infammation and augmentedregulatory immune response in ovalbumin-induced acute allergic airway inflammation withbetter preventive than therapeutic effects. Further investigations are needed to determine theminimal dose of infection that gives the best influence.
Trichinella spiralis
Helminthic therapy
Ovalbumin
Acute allergic airway inflammation
IL-6
IL-13
IL-10
FOXP3+ CD4+T cells
2020
08
01
401
412
https://jesp.journals.ekb.eg/article_113071_fe47464efd01190f781e5b14ac6bdec3.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
ANTIVIRAL EFFECT OF THE EGYPTIAN BEE VENOM (BV) AND ITS FRACTION (PLA2) ON INFLUENZA VIRUS: IN-VITRO STUDY
ABIR A.
ELFIKY
NORHAN M.
ELASMY
WALAA H.
SALAMA
AYMAN T. A.
MORSY
Influenza is a viral infection that attacks the respiratory system. For most people, the fludisappears on its own but sometimes the flu and its complications can be deadly. This studyestablished a new trend to treat Influenza virus by using bee venom and its fraction comparedwith the traditional flu drug. It was proved that bee venom (BV) has an antiviral effect. Thebee venom (BV), bee venom phospholipase A2 (BV-PLA2) and ribovinal as a control drugwere used. The cytotoxicity of the selected compounds was determined using MTT assay.Also, the cytopathic effect was measured after 24, 48 & 72 hours incubations anddetermination of gene expression of INF-gamma using SYBR Green. The IC50s of BV, BVPLA2and ribovinal were 87.8, 17.3 &137.5μg/ml after 24 hours incubation, 36.9, 9.6 &24.6μg/ml after 48 hours incubation, and 9.7, 7.45 & 31.6μg/ml after 72 hours incubation,respectively. In addition, the cytopathic effect of both BV and ribovinal was directlyproportional to its concentration and incubation time. Whereas, BV-PLA2 showed an increasein cytopathic effect after 48 hours in spite of its concentration in case of direct antiviral effect.However, the indirect antiviral effect for both BV and PLA2 showed the same cytopathiceffect in all concentrations and incubation times. So, the gene expression of INF-γ wassignificant increased after 48 hours incubation of either BV or ribovinal in direct and indirecteffects. While the INF-γ expression was (14.8 & 16.4) direct and in indirect antiviral effectsof BV-PLA2, respectively. These findings revealed the antiviral effect of both bee venom andBV-PLA2 against influenza virus.
2020
08
01
413
422
https://jesp.journals.ekb.eg/article_113077_a371d7d75673ed53ac1877588b6be2d9.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
EVALUATION OF MIDI PARASEP® FAECAL PARASITE CONCENTRATOR FOR THE DETECTION OF INTESTINAL PARASITIC INFECTIONS: A COMPARATIVE STUDY
MARWA O.
ABDEL AZIZ
EMAN M.
ABD EL-RAMAN
ENAS S.
EL-BAHAIE
Direct stool examination is the gold standard technique for diagnosing intestinal parasitic infection.Stool examination by stained smear, concentration techniques and sometimes culture are thecommonly used. The sensitivity of direct smear is low and requires repeated smears. Formalinethylacetate concentration method is more sensitive, but time consuming. Midi-Parasep® concentratoris a new diagnostic tool used as a routine stool examination for intestinal parasitic infectionsworldwide. There’s a lack of reports which evaluate the efficacy of Midi-Parasep® procedurein areas of limited diagnostic facilities and poor resource settings. Therefore, our currentstudy represents the first report that assessed the Midi-Parasep® technique by comparing its performanceto other economic standard measures like modified Ridley-Allen and formol detergentconcentration techniques for detection of intestinal parasites in human stool samples. We examined306 fecal samples using Midi-Parasep fecal parasite concentrator, modified Ridley-Allenconcentration and formol detergent concentration techniques. The best over-all sensitivity(71.7%) was obtained for Midi-Parasep technique followed by formol detergent concentration(66.7%) then modified Ridley-Allen technique (51.7%). Regarding, helminths parasites, the mostsensitive was formol detergent concentration technique (70%), followed by the Midi-Parasep < br />technique (60%), and Modified Ridley-Allen technique (33.3%). Referring to the intestinal protozoa,midi-Parasep technique had the highest sensitivity (83.3%), followed by modified Ridley-Allen procedure (70%) then formol detergent concentration technique (63.3%).
Stool examination
Parasites
Midi-Parasep®
Concentration methods
2020
08
01
423
430
https://jesp.journals.ekb.eg/article_113082_2db303cb46a47a2db59632c9a8ff8d72.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
LIVER HYDATID IN YOUNG AGE TREATED PER-CUTANEOUS BY USING PUNCTURE-ASPIRATION-INJECTION-REASPIRATION (PAIR) TECHNIQUE
EISSA ABDEL HAMED
IBRAHIM
AYMAN T. A.
MORSY
Human hydatid disease is mainly caused by infection with the larval stage of dog tapeworm Echinococcusgranulosus. The disease is widely endemic in many sheep and cattle rearing locales such asAustralia, Latin America, Africa and Middle Eastern countries, and now worldwide. Hydatidosis is aserious pathogenic, zoonotic and parasitic infection of humans, following ingestion of tapeworm eggsexcreted in the feces of infected dogs. Children of all age groups are susceptible from pet dogs (Urbanarea) or stray dogs (Rural area) and localization of the disease in the lungs is more commonly seen.Multiple liver cysts in the pediatric age group were relatively uncommon. Surgery remains the primarytreatment and the only hope for complete cure. PAIR is considered an alternative treatment forcystic echinococcosis (hydatid disease) and is often indicated for patients who do not respond to opensurgery or drugs.
Pediatric cases
Hydatidosis
Diagnosis
PAIR technique
Scolicidal agents
Follow-up
2020
08
01
431
438
https://jesp.journals.ekb.eg/article_113085_043394075aceb7c965090401946e7c92.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
IMPACT OF AMOEBIASIS AND GIARDIASIS ON TRACE ELEMENTS AMONG EGYPTIAN CHILDREN
AHMED M. S.
BAYOUMY
MOSTAFA E.
MOSTAFA
MOHAMED S.
FARAMAWY
WAFAA F. A.
AHMED
Giardia lamblia and Entamoeba histolytica are protozoan parasites causing marked morbidityin Egyptian children. A case-control random study was conducted from September to January2020 and included 49 children (1-18 years) attending Al Hussein University Hospital, Cairo,Egypt. They had amoebiasis (30 cases) and giardiasis (19 cases) and considered as the studygroup. Another 50 healthy persons were considered as a control group. All cases were subjectedto the estimation of serum levels of Zinc, Copper, and Iron.Serum Zinc level was significantly decreased in the infected group than the control group.The mean and standard deviation in the study group was 66.83±8.60 (amoebiasis was65.64±8.26 & giardiasis was 68.71±9.01) compared to the control group 95.67±8.34. SerumCopper was significantly increased in infected group than control group. The mean and standarddeviation was 129.93±19.45, for the amoebiasis was 130.63±20.17 and giardiasis was128.81±18.76 as compared to the control group 85.07±6.29.Serum Iron level was significantly decreased in the infected group than the control group. Themean and standard deviation in the study group was 50.63±5.23 (amoebiasis was 49.96±5.61 &giardiasis was 51.69±4.50) compared to the control group 82.87±9.28.
children
Amoebiasis
Giardiasis
trace elements
2020
08
01
439
446
https://jesp.journals.ekb.eg/article_113102_93cf892b65ea560720fd5940672c4361.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
ACCURACY OF MELD-NA SCORE AND OTHER NON-INVASIVE PREDICTORS OF ESOPHAGEAL VARICES STATUS IN EGYPTIAN PATIENTS WITH LIVER CIRRHOSIS
RASHA
MOHAMED
MOHAMED
SOLIMAN
WEAL S.
ELGHARABAWY
MANAL
MOHAMED
Esophageal varices (OV) are a serious and common complication of portal hypertension associatedwith liver cirrhosis. Hemorrhage from OV rupture is a life-threatening complication withhigh mortality. The model for end stage liver disease (MELD), MELD-Na+ scores are predictorsof non-transplant surgical mortality among patients with cirrhosis and has been a usefultool predicting the mortality in patients awaiting liver transplantation. As well, they have beensuggested in many studies as useful predictors of OV presence and severity.This study evaluated accurate cut-off values of MELD-Na and aspartate aminotransferase toplatelet count ratio index (APRI), AST/ALT (AAR), creatinine (ASR/Cr) as well as AST/ Bilirubin(AST/Bil.) ratios as new non-invasive predictors for liver cirrhosis patients.
patients
Esophageal varices
MELD score
APRI
AAR
Non-invasive predictors
platelet count
2020
08
01
447
452
https://jesp.journals.ekb.eg/article_113109_612e12e6fba621e058168b1095e36e8e.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
SMOOTH MUSCLE CELLS AND COLLAGEN FIBRES ARCHITECTURE IN EQUIVOCAL URETEROPELVIC JUNCTION OBSTRUCTION: ELECTRON MICROSCOPY STUDY WITH CLINICAL CORRELATION IN ADULT EGYPTIANS
MOHAMED
WISHAHI
AMR
ELKHOLY
MOHAMED H.
BADAWY
EHAB
HAFIZ
HOSSAM
ELGANZOURY
HANI H.
NOUR
MOHAMED A.
ISMAIL
AHMED S.
ZAYED
SAMIR
ELDAHSHAN
AHMED A.
MEHENA
TAREK
EL-LEITHY
Adult patients with ureteropelvic junction obstruction (UPJO) would undergo operative pyeloplastyor considered an equivocal type, the decision for management of equivocal UPJOwhether pyeloplasty or watchful follow-up is debatable. Equivocal UPJO referred to findingsand patient’ symptoms suggested an obstruction, whereas the diuretic renogram is not conclusiveto have a decision of pyeloplasty. This study evaluated the smooth muscle arrangement,distribution of collagen fibers, and presence of fibrosis in the UPJ segment in equivocal UPJOand normal UPJ segments using transmission electron microscopy (TEM) methods. The studydesign consisted of 30 adult Egyptian patients who underwent pyeloplasty for unilateral equivocalUPJO. Ten adult patients who had been operated on for oncological indications constitutedthe control group. Ten representative specimens of UPJO and 5 representative specimens of thecontrol group were examined by TEM. Clinical study comprised 30 patients having equivocalUPJO and operated upon with pyeloplasty were followed for 2 years. Retrospectively analysesof records of 42 adult patients who had unilateral equivocal UPJO and were on watchful followup < br />for 2 years was done to compare results of Pyeloplasty to watchful follow-up. Electron microscopystudy of UPJ segment of equivocal UPJO and the normal control cases showed similarfindings with proper arrangement of smooth muscle fibers that were in close contact to eachother, without fibroblast imposed between muscle bundles, and few collagen fibers were found.Clinical evaluation of results of pyeloplasty or watchful follow-up in equivocal UOJO in adultsshowed stable radiological findings, stable split renal function and diuretic renogram. In thewatchful follow-up group 12% of cases required pyeloplasty, indication for pyeloplasty wererepeated urinary tract infection, intolerable recurrent pain. The clinical series supported by ultrastructurefindings showed that watchful follow-up of equivocal UPJO was an accepted treatmentoption.
Ureteropelvic junction obstruction
hydronephrosis
Pyeloplasty
Ultrastructure
2020
08
01
453
458
https://jesp.journals.ekb.eg/article_113117_b136612a195e4aff922f90c8f7f4f696.pdf
Journal of the Egyptian Society of Parasitology
1110-0583
1110-0583
2020
50
2
DIAGNOSTIC AND THERAPUTIC CHALLENGE IN LIPOMATA AROUND SHOULDER GIRDLE
EISSA ABDEL HAMED
IBRAHIM
YASSER AHMED
EL SAYED
Lipoma is slow growing tumors and often occurs under the skin on the neck, shoulders,arms, back, abdomen and thighs. However, occasionally lipoma may be present in deep locationor originate within muscle.Lipoma affected only 1% of population, and commonly found in adults and is higher in manthan in women. The most common benign mesenchymal tumors composed of fat cell of adulttype, diffused or encapsulated type. Surgical removal is indicated when causing trouble assite, size, appearance and presence of pain. The study was carried on 35 male patients presentedby lipoma around shoulder girdle operated in Kobry El-Kobba Military Medical Campus.The patients were divided into four groups, G1:25 patients with primary subcutaneous lipoma,G2: 8 patient with subscapular lipoma, G3: 1 patient with giant submascular left shoulderlipoma, and G4: 1 patient with giant subscapular lipoma “diagnosed before operation”including complete surgical excision was done under general anesthesia in all the patientswithout any recurrence.
Lipoma
Shoulder girdle
Shoulder joint movement
2020
08
01
459
466
https://jesp.journals.ekb.eg/article_113118_156281e57b3d91d5572cb7f830071dea.pdf